复感康颗粒质量控制方法研究  

Study of Quality Control Method for Fugankang Granules

作　　者：覃伟[1] 赵春景[1] 

机构地区：[1]重庆医科大学附属第二医院药剂科,重庆市400010

出　　处：《中国药房》2005年第16期1255-1257,共3页China Pharmacy

摘　　要：目的:建立复感康颗粒的质量控制方法。方法:采用薄层色谱法对复感康颗粒中黄芪、白术、陈皮进行定性鉴别;采用高效液相色谱-蒸发光散射检测器法测定复感康颗粒中黄芪甲苷的含量。结果:在薄层色谱中可鉴别出黄芪、白术、陈皮;黄芪甲苷进样量在1.306μg～13.060μg范围内线性关系良好(r=0.9997),平均加样回收率为97.62%(RSD=1.72%)。结论:本方法简便、准确、重现性好,可用于复感康颗粒的质量控制。OBJECTIVE：To establish the quality control method for fugankang granules.METHODS：Radix Astragali ,Atractylodes Macrocephala, Pericarpium Citri Reticulatae in fugankang granules were identified by TLC and the content of astragaloside in fugankang granules was determined by HPLC- ELSD method.RESULTS： Radix Astragali, Atractylodes Macrocephala, Pericarpium Citri Reticulatae could be identified by TLC; Astragaloside showed good linear relationship within the range of 1.306μg-13.060μg （ r = 0.9 997）, the average recovery was 97.62 % （RSD = 1.72 % ）. CONCLUS ION ： The method is simple,accurate and with good reproducibility，which can be used as quality control for fugankang granules.

关 键 词：复感康颗粒 质量控制 薄层色谱法 高效液相色谱-蒸发光散射检测器法 

分 类 号：R927.11[医药卫生—药学]