甘草麻黄碱片的质量控制方法研究  

Study on the Quality Control Method of Glycyrrhiza Ephedrine Tablets

作　　者：黄璐敏[1] 简淑娟[1] 

机构地区：[1]广东惠州市药品检验所,惠州市516008

出　　处：《中国药房》2005年第16期1259-1260,共2页China Pharmacy

摘　　要：目的:建立甘草麻黄碱片的质量控制方法。方法:采用薄层色谱法对甘草麻黄碱片中甘草进行定性鉴别;采用高效液相色谱法测定甘草麻黄碱片中盐酸麻黄碱含量。结果:在薄层色谱中能检测出甘草;盐酸麻黄碱检测浓度在0.502～7.530μg/ml范围内呈良好的线性关系(r=0.9998),平均加样回收率为98.80%(RSD=0.42%)。结论:本方法可用于甘草麻黄碱片的质量控制。OBJECTIVE： To establish the quality control method for glycyrrhizia ephedrine tablets.METHODS： The glycyrrhiza in glycyrrhiza ephedrine tablets was identified by TLC and the content of ephedrine hydrochloride in the tablets was determined by HPLC.RESULTS： Glycyrrhiza could be detected in TLC; Good linear relationship was achieved when the determination concentration range of ephedrine hydrochloride was 0. 502-7. 530μg/ml（ r= 0.9 998）, the average recovery rate was 98.80% （RSD = 0.42% ） .CONCLUSION：The method can be used as quality control for glycyrrhiza ephedrine tablets。

关 键 词：甘草麻黄碱片 甘草 盐酸麻黄碱 薄层色谱法 高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]