LADA患者血清IL-12、IL-18及血淋巴细胞亚群研究  

Study on blood IL-12, IL-18 and lymphocyte subsets in LADA patients

作　　者：邬磊[1] 刘鹏鹰[1] 李明[1] 张琼丽[1] 楼谨[1] 黄晖[1] 李呐[1] 余怀新[1] 

机构地区：[1]深圳市第二人民医院综合科,518026

出　　处：《中华内分泌代谢杂志》2005年第4期335-336,共2页Chinese Journal of Endocrinology and Metabolism

基　　金：广东省医学科学技术研究基金(A2001626)

摘　　要：与2型糖尿病组及正常对照组相比,成人隐匿性自身免疫糖尿病(LADA)组外周血淋巴细胞亚群有明显变化,白细胞介素12(IL12)、白细胞介素18(IL18)水平亦升高。LADA存在明显细胞免疫紊乱,并与胰岛功能密切相关。T lymphocyte subsets in LADA group were obviously different with those in type 2 diabetes and control groups. Serum IL-12,IL-18 levels in LADA group were higher than those in type 2 diabetes and control groups. There existed significant correlation between immunologic derangement and dysfunction of pancreatic islet in LADA patients.

关 键 词：血淋巴细胞亚群 成人隐匿性自身免疫糖尿病 白细胞介素12 白细胞介素18 

分 类 号：R587.1[医药卫生—内分泌]