血小板衍化生长因子B在糖尿病大鼠肾皮质中的表达  

Expression of PDGF-B in renal cortex of diabetic rat

作　　者：隋春华[1] 吴万龄[1] 洪金秧[2] 张惠新[2] 

机构地区：[1]上海第二医科大学附属第九人民医院内分泌科,200011 [2]上海第二医科大学附属第九人民医院中心实验室,200011

出　　处：《中华内分泌代谢杂志》2005年第4期374-375,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：本研究以半定量RT-PCR法测定了糖尿病及对照Wistar大鼠肾皮质血小板衍化生长因子B(PDGFB)mRNA水平,发现糖尿病大鼠为对照组2.5倍,提示PDGFB在糖尿病肾病中起一定作用。Expression of platelet-derived growth factor （PDGF）-B mRNA was measured by semiquantitative RT-PCR in renal cortex of diabetic and control Wistar rats. The expression of PDGF-B mRNA in renal cortex of diabetic rats was 2.5-fold of normal rats, suggesting that PDGF-B seems to play a role in diabetic nephropathy.

关 键 词：血小板衍化生长因子B 糖尿病 大鼠 肾皮质 基因表达 细胞生长因子 

分 类 号：R587.2[医药卫生—内分泌]