单纯性收缩期高血压患者的亚临床炎症状态  

Subclinical inflammation in simple systolic hypertension.

作　　者：王一尘[1] 方根强[1] 张来娣[1] 

机构地区：[1]上海第二医科大学附属新华医院老年病科,上海200092

出　　处：《中国综合临床》2005年第10期867-868,共2页Clinical Medicine of China

摘　　要：目的探讨单纯性收缩期高血压患者的亚临床状态及其与血压高低的关系。方法采用分组对照研究方法,测量80例单纯性收缩期高血压患者(研究组)的超敏C-反应蛋白(Hs-CRP)水平,并与80例血压正常且年龄、性别与研究组匹配者(正常对照组)进行对照比较。根据80例单纯性收缩期高血压患者收缩压高低进一步分为3组,同时对血清Hs-CRP水平进行比较。结果研究组的血脂及Hs-CRP水平与正常对照组比较差异均有显著性,研究组中平均收缩压高低与Hs-CRP成正比关系。结论单纯性收缩期高血压患者存在亚临床炎症状态,且与收缩压高低有相关性。Objective To investigate the.relationship between subclinical inflammation patients and the blood pressure. Methods Serum levels of C-reactive protein （Hs-CRP） were measured in a cross-sectional study involving 80 simple systolic hypertension patients （ research group ） and 80 normotension controls matched in age and sex（ normal control group）. The research group was divided into three subgroups according to the levels of blood pressure whose serum levels of Hs-CRP was compared. Results The blood lipid and Hs-CRP levels in research group were significantly different from those in control group. The mean systolic blood pressure was positively correlated with Hs-CRP in three subgroups of research group. Conclusion Subclinical inflammation exists in simple systolic hypertension patients ,which is correlated with the systolic hypertension level.

关 键 词：单纯性收缩期高血压 C-反应蛋白 

分 类 号：R544.1[医药卫生—心血管疾病]