C-反应蛋白在不稳定型心绞痛病人中的变化和意义  

The significance of C-reactive protein changes in patients with unstable angina

作　　者：李文广[1] 

机构地区：[1]深圳市第二人民医院,广东深圳518029

出　　处：《中国实验诊断学》2005年第4期559-560,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的了解C-反应蛋白(C-reactiveprotein,CRP)在不稳定型心绞痛病人中的发病机制和对预后的判断。方法通过测定32例不稳定型心绞痛病(Unstableangina,UA)和30例稳定型心绞痛(Stableangina,SA)病人血清中CRP的含量并相互比较,观察住院期间和随访6个月的心血管事件的发生率。结果不稳定型心绞痛病人组CRP含量为(10.52±2.01)mg/L,而稳定型心绞痛病人组为(2.11±0.38)mg/L,相比有着非常显著的差异(P=0.004)。结论伴有CRP升高的UA病人心绞痛发生的次数比SA病人明显增多(P=0.007),且心肌梗死及猝死的发生率高于SA组。Objective The purpose is to observe the function of C-reactive protein（CRP） in the mechanism and prognostic judgement of unstable angina. Methods We measure the content of CRP in patients with unstable angina（ n = 32） and stable angina （ n = 30） and observe the cardiac occurrence during the hospitalization and random sample（6 months）. Results There was significant difference in content of CRP hetween group of unstable angina（10.52 ± 2.01 mg/L） and group of stable angina（2.11 ± 0.38 mg/ L）. Conclusion The patients of unstable angina with increased CRP have more occurrence of angina than those of stable angina（ P = 0.007） and have higher frequency of myocardial infarction and sudden death.

关 键 词：C-反应蛋白 不稳定型心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]