结核菌糖脂抗原(TBGL)412例临床应用研究  

412 cases control clinical study on Tuberculosis Glycolipids (TBGL)

作　　者：张国龙[1] 杜长梅[1] 高飞絮[1] 石瑞如[1] 王江东[1] 张霞[1] 秦殊[1] 王伟[1] 

机构地区：[1]河南省胸科医院,郑州市450003

出　　处：《中原医刊》2005年第16期1-2,共2页Central Plains Medical Journal

摘　　要：目的评价新型结核病血清学诊断试剂结核菌糖脂抗原(TBGL)的临床应用价值。方法研究共收选412病人,包括结核病人105例,其它呼吸系统疾病153例(包括肺炎,支气管扩张,肺癌,上呼吸道感染等),其它肺外疾病104例,抗结核菌抗体测定采用双盲法,操作按说明书进行。结果①TBGL的特异度为88.6%,灵敏度为79.0%。②TBGL阳性检出率有明显的年龄组差别。结论TBGL可以作为一种结核病血清学指标,为临床提供诊断依据。Objective To evaluate a new tuberculosis serodiagnosis reagent of Tuberculosis Glycolipids （TBGL）. Methods 412 cases enrolled in study including 105 active TB cases,153 non-tuberculosis respiratory disease cases （including pneumonia, bronchiectasis, lung cancer, upper respiratory tract infection）. Examination has been done in double-blind. Operation follows the handbook introduction. Results ①The specificity of TBGL is 88.6%. Sensitivity is 79.0%. ②TBGL positive detection rate has a significant difference in different age groups. Conclusion TBGL can be used as a maker to diagnose tuberculosis.

关 键 词：结核 诊断 结核茵糖脂抗原 临床应用研究 糖脂抗原 结核菌 血清学诊断试剂 结核病人 临床应用价值 呼吸系统疾病 

分 类 号：R446.61[医药卫生—诊断学]