部分脾栓塞治疗肝硬化门静脉高压脾功能亢进  

Treatment of hypersplenia secondary to portal hypertension with partial splenic embolization

作　　者：丁其扬 郁启生 王钧镕[1] 孙琳[1] 

机构地区：[1]上海市普陀区中心医院感染科,上海200062

出　　处：《世界感染杂志》2005年第4期326-327,344,共3页World Journal of Infection

摘　　要：目的评价部分脾栓塞治疗肝硬化门静脉高压脾功能亢进的临床价值。方法采用Seldinges技术经股动脉插入myashinas导管至脾动脉主干进入脾门部，用明胶海绵颗粒进行部分栓塞。结果15例术后外周血白细胞和血小板数均回升，随访3个月仍在正常范围。门静脉，脾静脉回缩，凝血酶原活动度（PTA）上升，血氨下降，未出现严重并发症。结论部分脾栓塞是治疗肝硬化门静脉高压脾功能亢进安全、有效的方法。Objective To evaluate the clinical efficiency of partial splenic embolization （PSE） treatment on patients with portal hypertension and hypersplenia caused by cirrhosis. Method The myashinas duct was inserted into the splenic artery stem via the femoral artery by the seldinges technology and PSE was performed with particulate gelatin sponge. Results All 15 patients who were treated with PSE presented increased peripheral blood leukocyte and platelet counts after surgery and remained in normal ranges during a 3-month follow up. The diameter of splenic vein and portal vein was contracted to normal. The prothrombin activity increased, the level of blood ammonia lowered with no severe complications happened after treatment. Conclusion PSE is safe and effective in treating portal hypertension and hypersplenia caused by cirrhosis.

关 键 词：部分脾栓塞 肝硬化 脾功能亢进 

分 类 号：R657.63[医药卫生—外科学]