性滥人群庚型肝炎病毒感染状况  

The Prevalence of HGV in Prostitutes

作　　者：陈红云 张振纲[1] 田德英 夏宁邵[2] 黄加权[1] 黄元成 雷洪波 杨道锋 

机构地区：[1]华中科技大学同济医学院附属同济医院,武汉430030 [2]厦门大学国家基因工程重点实验室

出　　处：《内科急危重症杂志》2005年第4期166-167,共2页Journal of Critical Care In Internal Medicine

基　　金：国家863课题资助(102-07-02-07)

摘　　要：目的:调查湖北地区性滥人群庚型肝炎病毒(HGV)感染状况。方法:检查309例有性滥史者的血清HGV感染标志物,用ELISA方法检测抗HGV。结果:309例性滥者HGV的感染率11.97%(37例),显著高于普通人群(1.51%,19/1257例)。女性HGV的感染率(12.36%,32/259例)与男性HGV的感染率(10%,5/50例)无显著差异。性滥时间大于2年者抗HGV阳性率17.05%(30/176例)显著高于性滥时间小于2年者5.26%(7/133例)。女性中有吸毒史者的HGV感染率(22.37%,17/76例)显著高于未吸毒者(8.20%,15/183例)。所有HGV感染者的肝功能正常。结论:性滥人群具有较高的HGV感染率,HGV可能通过性途径传播。性滥人群HGV的感染率与性滥时间呈正相关,吸毒增加了性滥者HGV感染的风险。Objective： To survey the prevalence of HGV among prostitutes. Methods： Anti-HGV were detected by ELISA. Results ： The positive rate of HGV markers in prostitutes was 11.97%（37/309）. The positive rate of Anti-HGV in prostitutes was higher than that in normal population （1.51% ,19/1257）, （X^2 = 74. 03,P〈0. 01）. There were no difference of the positive rate of anti-HGV between female and male （X^2 = 0. 05, P〉0. 05）. However , notable difference was found between prostitutes prostituted for more than 2 years（17. 05%）and those prostituted for less than 2 years （5.06%, X^2 = 8.89, P〈0. 01 ） ; The positive rate of Anti-HGV in prostitutes with drug addiction（22.37%） was higher than that in prostitutes without drug addiction（8. 20%,X^2 =8. 69,P〈0. 01 ） . No abnormality of liver function was found in all of the cases with positive HGV markers. Conclusions： prostitution increases the risk of HGV infection.

关 键 词：庚型肝炎病毒 性滥 流行病学 

分 类 号：R557[医药卫生—血液循环系统疾病]