中药花色素类成分抗癌研究进展  

Progress in research on anthocyanidin components in Chinese traditional medicine against neoplasm

作　　者：林晓霞[1] 朱寿民[2] 

机构地区：[1]浙江大学医学院附属邵逸夫医院,浙江杭州310016 [2]浙江大学医学院,浙江杭州310006

出　　处：《中国中药杂志》2005年第15期1147-1150,共4页China Journal of Chinese Materia Medica

基　　金：科学技术部科技中小企业技术创新基金(2004D40165)

摘　　要：花色素是一类分布十分广泛的植物色素,在中草药材中也普遍存在。作者综述花色素抗癌试验的最新研究进展,包括抗氧化、抗DNA断裂,促使细胞分化、细胞凋亡,干扰细胞生长调节,抗血管生成功能等,以及它们的抗癌机理和构效关系,指出花色素药物研发的前景。Anthocyanidin is a type of the plant pigments distributed very extensively, in traditional Chinese herbal products as well. In this review was introduced the recently progress in the anti-cancer trials of anthocyanidins, including the anti-oxidation, the prevention of DNA strand scission, stimulation of cell differentiation, induction of cell apoptosis, interference of regulation of cell proliferation, anti-angiogenic property etc, and the research of anti-cancer mechanisms of anthocyanidin and its structure-activity relationship, pointed the foreground of research and development of anti-cancer medicine.

关 键 词：花色素 花色素苷 抗癌机理 构效关系 

分 类 号：R285[医药卫生—中药学]