氨力农治疗充血性心力衰竭的临床观察  

Clinical investigation of the effects of amrinone on congestive heart failure

作　　者：陈学林[1] 张银环[1] 涂源淑[1] 韩继媛[1] 李明慧 

机构地区：[1]同济医科大学心血管病学研究所,武汉430022

出　　处：《临床心血管病杂志》1995年第2期83-84,共2页Journal of Clinical Cardiology

摘　　要：观察使用新的正性肌力药氨力农治疗80例充血性心力衰竭(CHF)的疗效,结果心功能得到改善,显效率66.25%,总有效率95.00%.其中按常规强心、利尿、扩管治疗无效的20例难治性CHF,血浆儿茶酚胺、去甲肾上腺素、肾上腺素水平治疗前后有显著差异(P<0.01).提示氨力农治疗CHF及难治性CHF临床疗效肯定.Amrinone,a new positive inotropic drug,was used for the treatment of sixty patients with congestive heart failure and twenty patients with refractory heart failure. The total response to amrinone was 95. 00% ,and 66. 25% of them got significant improvement. In the group of refractory heart failure we found that the blood levels of catecholamine, norepinephrine and epinephrine after the treatment were markedly reduced in contrast to that before the treatment. No obvious side-effect was found in our observation. We conclude that this drug can play a useful role in the management of congestive heart failure,include refractory heart failure.

关 键 词：氨力农 充血性 心力衰竭 儿茶酚胺 药物疗法 

分 类 号：R541.610.5[医药卫生—心血管疾病]