早期缺血心肌内肌酸激酶变化的病理学研究  

A pathological research of the creatine kinase changes in early ischemic myocardium

作　　者：温祥云[1] 李文[1] 陈铁军[1] 

机构地区：[1]首都医科大学病理学教研室

出　　处：《临床与实验病理学杂志》1995年第3期221-223,共3页Chinese Journal of Clinical and Experimental Pathology

摘　　要：对实验性缺血的大鼠心肌切片进行免疫组化染色，检测肌酸激酶。结果显示，在心肌缺血４０ｍｉｎ后，着色开始呈现酶活性减少的变化，并随缺血时间延长而更加明显。实验证实肌酸激酶的免疫组化染色，是一种诊断早期心肌缺血的特异性强、敏感性高的重要辅助方法。The immunohistochemical stain for estimating creatine kinase was made in the experimental myocardial ischemic sections of rats, the results showed that the color change of enzymatic activitic decrease occurred after 40 min ischemia, and this phenomena became more prominent accompany by extension of ischemic time. This experimemt proved that the creatine kinase PAP staining method is an important supplemental method and has higher specificity and sensitivity for early myocardial ischemia.

关 键 词：心肌缺血 肌酸激酶 免疫组化 染色 病理学 

分 类 号：R541.402[医药卫生—心血管疾病]