鬼臼乙叉甙诱导小鼠脾淋巴细胞程序化死亡的实验研究  

PROGRAMMED CELL DEATH OF MOUSE SPLEEN LYMPHOCYTES INDUCED BY ETOPOSIOE IN VITRO

作　　者：吴学宾[1] 黄晓明[1] 陈宝安[1] 金宝翠[1] 胡向阳[1] 高峰[1] 

机构地区：[1]南京铁道医学院血液病学研究室

出　　处：《南京铁道医学院学报》1995年第3期148-150,共3页Journal of Nanjing Railway Medical College

摘　　要：鬼臼乙叉甙（ｅｔｏｐｏｓｉｄｅ，ＶＰ１６）体外实验诱导小鼠脾淋巴细胞程序化死亡并与自然死亡组和正常对照组比较，表明ＶＰ１６诱导组与自然死亡组所致的ＰＣＤ结果是一致的。本实验建立了程序化细胞死亡研究的实验方法。PCD(Programmed cell death)of mouse spleen lymphocytes in vitro was induced by etopo-side(VP16)and was compared with natural death and that of normal control.Afeature of PCDwas similar found in natural death and VP-16-induced cells. An experiment method was estab-lished for studying PCD of leukemia further.

关 键 词：程序化细胞死亡 鬼臼乙叉甙 脾淋巴细胞 

分 类 号：R329.25[医药卫生—人体解剖和组织胚胎学]