扩张型心肌病左心功能改变的特征  

Characteristics of the Left Ventricular Dysfunction in Patients with Dilated Cardiomyopathy

作　　者：李汉康 廖静 李志林 丁荣华 马文珠 

出　　处：《南京医科大学学报（自然科学版）》1995年第4期765-767,共3页Journal of Nanjing Medical University(Natural Sciences)

摘　　要：采用心机械图法，测定２０２名正常人和５８例扩张型心肌病（ＤＣＭ）２项收缩性指标和５项舒张性指标。结果证明ＤＣＭ的心力衰竭属收缩和舒张混合型，在ＤＣＭ早期射血分数就已明显减低（０．７５和０．６４，Ｐ＜０．０１），其降幅与临床心功能不全的程度相一致，反映左室舒张性的多项指标与心衰症状的出现相关联（Ｐ＜０．０１），ＤＣＭ的晚期病例提示有心室“过度”顺应现象。In order to evaluate left ventricular(LV)properties in patients with dilated cardiomyopathy(DCM) the LV systolic variable, LV ejection fraction (LVEF) and the LV diastolic variables, total relaxation time index(TRTI) reflecting LV relaxation and ratio of A wave to diastolic amplitude in apex tracing(A/D) reflecting LV compliance were measured by mechanocardiography in 202 normal subjects and 58 patients with cardiomyopathy.The results demonstrated that congestive heart failure(CHF) associated with DCM was systolic dysfunction combined with diastolic one, In the early stage, decreased LVEF in the patients with DCM as compared with the normal subjects was shown(0.75vs 0. 64.P<0. 01) even without any clinical symptoms. The level of reduced LVEF in DCM correlated with the severity in CHF. There was a strong correlation between the changes in the variables reflecting LV diastolic function and the presence of clinical symptoms in CHF(P<0. 01). The results also suggest that in terminal stage there is an 'over' compliance of left ventricle in the patients with DCM, The authors conclude that monitoring LV systolic and diastolic function in patients with DCM may help the physicien to early diagnosis and objectively to estimate development and prognosis in DCM.

关 键 词：心肌疾病 心脏功能试验 心机械图 

分 类 号：R542.2[医药卫生—心血管疾病]