钼缺乏和亚硝酸盐中毒在克山病发病中作用的研究  

PATHOGENETIC ROLE OF MOLYBDENUM DEFICIENCY AND NITRITE POISONING IN KESHAN DISEASE

作　　者：盖晓东[1] 

机构地区：[1]白求恩医科大学地方病研究所

出　　处：《中国地方病防治》1989年第5期267-270,共4页Chinese Journal of Control of Endemic Diseases

摘　　要：本文报道了钼缺乏和亚硝酸盐中毒对大鼠心肌坏死的影响。结果表明,在亚硝酸盐中毒情况下,钼块乏大鼠心肌坏死检出率及坏死面积均明显高于补钼组,代表心肌损伤的血清磷酸肌酸激酶活性也明显增高。这为探索低钼及亚硝酸盐过多与克山病病因关系提供了实验依据。The effects of molybdenum deficiency and nitrite poisoning on the myocardial necrosis of rats are reported in this article. These results show that the incidence and the area of myocardial necrosis in molybdenum deficiency rats were higher than that in control. The Content of serum phosphocreatine Kinase (CK)in molybdenum deficiency rats also increased. These results provide the experimental basis for probing into the etiology of Keshan disease.

关 键 词：克山病 钼缺乏 亚硝酸盐中毒 

分 类 号：R542.302[医药卫生—心血管疾病]