切除内脏大神经大鼠的低氧红细胞反应及EPO效应观察  

EFFECTS OF EPO AND ERYTHROPOIESIS ON THE RATS SPLANCHNIC NEURECTOMIZED FOLLOWED BY HYPOXIA

作　　者：孟宪法[1] 许存和[1] 于洪九 徐仲崎[1] 

机构地区：[1]大连大学医学院

出　　处：《青海医学院学报》1995年第4期1-2,共2页Journal of Qinghai Medical College

基　　金：省科委;省卫生厅"八五"攻关项目

摘　　要：本文观察了切除内脏大神经对红细胞参数的影响。结果表明，切除内脏大神经大鼠低氧时的红细胞参数改变与单纯低氧对照比较，无显著性差异。切除内脏大神经也不影响大鼠低氧时的红细胞生成EPO效应。实验提示，在动物低氧红细胞生成反应中，植物神经系统的内脏大神经途径无重要调控作用。The effects of section of splanchnic nerves on the erythropoietic parameters has been investigated. The results suggested that the erythropoiesis in rats having bilateral splanchnic neurectomy was not significantly different from in intact rats when subjected to hypoxic hypoxia. It was not affected cutting the nerves for EPO effect on erythropoietic response during hypoxia. The autonomic nervous system does regulate the erythropoietic response to hypoxic hypoxia via the splanchnic nerves.

关 键 词：内脏大神经 红细胞生成 促红细胞生成素 低氧 

分 类 号：R338.5[医药卫生—人体生理学]