冠心病血清硒、超氧化物歧化酶及超弱发光的观测研究  

INVESTIGATION OF BLOOD SELENIUM, SUPEROXIDE DISMUTASE, SERUM ULTRAWEAK CHEMILUMINESCENCE IN PATIENTS WITH CORONARY HEART DISEASE

作　　者：钟明 徐庆来 张薇 侯彬 秦绪光 

出　　处：《山东医科大学学报》1995年第1期46-48,共3页Acta Academiae Medicinae Shandong

摘　　要：测定２０例正常人和３０例冠心病患者血清自发化学发光（ＳＣＬ）和鲁米诺诱导发光（ＬＣＬ），并测定了血清硒（Ｓｅ）、脂质过氧化物（ＬＰＯ）和红细胞超氧化物歧化酶（ＳＯＤ）活性。冠心病患者血清ＬＰＯ、ＳＣＬ和ＬＣＬ明显高于正常对照组（Ｐ＜０．０１），血清Ｓｅ和红细胞ＳＯＤ活性明显低于正常对照组（Ｐ＜０．０１），多因素逐步分析结果显示冠心病与血清Ｓｅ呈明显负相关，与ＬＰＯ、ＳＣＬ和ＬＣＬ呈明显正相关。Spontaneous chemiluminescence (SCL), luminal chemiluminescence (LCL), serum lipoperoxide (LPO), blood selenium (Se) and erythrocyte superoxide dismutase (SOD) activity were determinend in 30 patients with coronary heart disease (CHD group) and 20 healthy subjects (control group).The results indicated that there was statistically significant increase of LPO. SCL. LCL, and statistically significant decrease of Se and SOD activities in CHD group as compared with control group. The stepwise regression analysis showed that there is (1) a negative correlation between Se and CHD; (2) a positive correlation between LPO, SCL, LCL and CHD

关 键 词：冠心病 血清 超弱发光 过氧化脂质 硒 

分 类 号：R541.402[医药卫生—心血管疾病]