促黄体素释放激素（LRH）抗原对公雏免疫去势效果的研究  

EFFECTS OF LEUTEINITING HORMONE RELEASING HORMONE ANTIGENON IMMUNE CAPONIZATION IN COCKEREL CHICKS

作　　者：辛长砺[1] 周于奋[1] 李绪英[1] 辛志先 田永青 

机构地区：[1]山西农业大学,山西省兽医生物药品制造厂,太谷县动物检疫站

出　　处：《山西农业大学学报》1995年第1期13-17,共5页

摘　　要：制备促黄体素释放激素（ＬＲＮ）抗原乳剂，给１０日龄公雏注射后，每周称体重，测鸡冠厚、高、长度，第２０周屠宰，称们体重及睾丸重。试验结果表明，ＬＲＨ抗原无论加入弗氏佐剂或氢氧（也铝佐剂，只要达到一定注射剂量（首次量１０μｇ／只，二次量加倍），就可产生明显的免疫去势效果，即鸡冠及睾九生长变慢，试验组与对照组比较差异十分显著（Ｐ＜０．０１）；体重增长加快，试验组与对照组比较，在第４、８、２０周平均体重和宰后胴体重差异十分显著（Ｐ＜０．０１）或显著（Ｐ＜０．０５）。而ＬＲＨ首次注射剂量为５μｇ／只的试验组与对照组比较，上述各项指标均无显著差异（Ｐ＞０．０５）。Ten age in days cockerel chicks were injected leuteiniting hormone releasing hormone(LRH) antigen emulsion. The liveweight, testes weight and the height, lenght and thickness of comb were measured weekly, and the weight of ketone body and testes post -slaughter after a 20 week infusion of LRH were measured. Adequate injection dosage LRH adding Freund's adjuvant or aluminum hydroxide adjuvant had significant immune caponization effect on cockerel chicks. When the first and second dose was 10μg/per chick and 20μg/per chick respectively, the comb and testes in grouning rates of experiment group were lower (p<0.01) and weight gain were higher than that of control group, the average liveweight at 4, 8, and 20 week and ketone body weight of experiment group were higher than that of control (p<0.05 Or p<0.01). When the first dose was 5μg/per chick, the above indexes were not significant between injected and control group.

关 键 词：促黄体素释放激素抗原 免疫去势 公雏 

分 类 号：S831.1[农业科学—畜牧学]