乙肝病毒DNA阳性患儿家族成员的调查  

Prevalence of HBV-DNA in Family Members of HBV-DNA Positive Children

作　　者：孔梅 徐伟人[1] 

机构地区：[1]上海市卢湾区中心医院儿科,上海第二医科大学附属第九人民医院检验科

出　　处：《上海第二医科大学学报》1995年第4期338-340,共3页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：本文对１４例ＨＢＶ－ＤＮＡ阳性患儿的家庭成员２３人进行血清学检测，并收集２２例正常人血清为对照组。２３例家庭成员中ＨＢＶ－ＤＮＡ阳性率为３４．８％（８／２３），明显高于对照组４．５％（１／２２），Ｐ＜０．０１。ＨＢＶ－ＤＮＡ阳性率在患儿的双亲为４０％（４／１０），而在其祖父母辈为３３．３３％（３／９），二者无显著差异（Ｐ＞０．０５）。提示乙肝病毒感染的家庭聚集性存在双亲或祖父母辈与患儿间的易感性相似。Twenty three family members of 14 HBV-DNA positive children and 22 donor controls had their serum tested by PCR for the presence of HBV-DNA. The HBV-DNA positive rate of family members was 34.8%,significantly higher than that of donor controls (4.5%)(P<0.01). The HBV-DNA positive rates of parents and grandparents were 40%and 33/33%, respectively (P>0.05). These results demonstrated that there was a clustering of HBV infection in families of HBV-DNA positive children.

关 键 词：乙型肝炎病毒 家庭内 病毒传播 疾病统计 

分 类 号：R725.126[医药卫生—儿科]