灵苓胶囊对小鼠特异性抗体和肿瘤坏死因子产生以及抗S_(180)肉瘤的作用  被引量:10

Effect of Ling-Ling Capsule on Antibody Production,Tumor Necrosis Factor and Anti-S_(180) Sarcoma

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作  者:王冠福[1] 李伟毅[1] 张敏[1] 程丽萍[1] 陈广洁[1] 孙福梅[1] 朱云凤[1] 

机构地区:[1]上海第二医科大学基础医学院,上海第二医科大学免疫学教研室

出  处:《上海免疫学杂志》1995年第4期233-235,共3页Shanghai Journal of Immunology

摘  要:本文报道灵苓胶囊对Balb/c小鼠能明显提高血清特异性抗体凝集效价,显著促进腹腔巨噬细胞在细菌内毒素诱导下产生肿瘤坏死因子。此外,对小鼠S180肉瘤具有较强的抑制作用,与环磷酸胺合用能提高其抑瘤率。Immunomodulation effect of Ling-Ling Capsule of antibody production of mouse B lymphocyte and activity of tumor necrosis factor of mouse macrophageas well as anti-S180 sarcoma were studied.It was proved that there were significantlyincreasing in antibody titer and activity of tumor necrosis factor.In addition,there was obviously enhancing antitumor effect on S180 sarcoma, and it could elevate antitumor activity with cyclophosphamide.

关 键 词:灵苓胶囊 肿瘤坏死因子 抗肿瘤作用 动物实验 

分 类 号:R285.5[医药卫生—中药学]

 

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