猫隔核在刺激内脏大神经诱发皮质醇浓度增高中的作用  

PARTICIPATION OF SEPTUM ON THE INCREASE OF PLASM CORTISOL LEVEL INDUCED BY STIMULATION OF THE GREATER SPLANCHNIC NERVE OF CAfS

作　　者：周予谦[1] 朱晓蔓[1] 朱子涛[1] 郭建侃 胡立明[1] 周伟君[1] 

机构地区：[1]南京铁道医学院生理教研室,南京大学生物学系,南京铁道医学院同位素室

出　　处：《生理学报》1995年第3期287-291,共5页Acta Physiologica Sinica

摘　　要：采用健康成年猫３６只，电刺激左侧内脏大神经中枢端，可引起血浆皮质醇浓度升高，损毁隔核后，这升高效应消失，说明隔核可能参与诱发皮质醇升高效应过程。隔核内微量注射心得安，也可使升高效应消失，但注射酚妥拉明则无变化。上述结果提示，隔核参与肾上腺皮质分泌功能的调节，可能是通过去甲肾上腺素（ＮＥ）能系统中的β受体来实现的。Experimens were performed on 36 cats, showing that stimulation of the central end of the left major splanchnic nerve induced an increase of the plasma cortisol level. The centripetal effect was abolished by lesioning the septal nuclei, just as the same as injection of propranolol into the nuclei ; but phentolamine had no such preventive action.All the findings show that it is the noradrenergic β-receptor system of the septal nuclei that exerts a considerable effect on cortisol secretion.

关 键 词：隔核 内脏大神经 皮质醇 

分 类 号：R338.26[医药卫生—人体生理学]