豚鼠在体肠系膜下神经节细胞兴奋的来源  

THE EXCITING ORIGIN OF GUINEA-PIG INFERIOR MESENTERIC GANGLION NEURONS in vivo

作　　者：史明仪[1] 周华珠[1] 蒋志根[1] 

机构地区：[1]扬州医学院生理教研室,皖南医学院电生理研究室

出　　处：《生理学报》1995年第3期301-304,共4页Acta Physiologica Sinica

基　　金：国家自然科学基金

摘　　要：本文运用在体细胞内记录法，观察了与肠系膜下神经节（ＩＭＧ）相连的四组神经对ＩＭＧ神经元电位活动的影响。结果显示切断或阻滞任一组神经均使ＩＭＧ细胞电活动受抑。其中结肠神经（ＣＮ）和腹下神经（ＨＮ）分别传导源自结肠尾段和膀胱等盆腔脏器的外周性兴奋，节间神经（ＡＭＮ）同时传导源自脊髓的中枢性和结肠的外周性兴奋。定量研究表明外周比中枢的影晌更重要。因此ＩＭＧ不仅是传统认为的“信息传递站”，而且对中枢和外周信息有整合作用。Intracellular recording in vivo showed that spontaneous activities of guinea-pig inferior mesenteric ganglion (IMG) neurons were inhibited when any one of the four groups of the nerves connected to the IMG was cutted or blocked, indicating that all the four groups of nerves sent in excitutory input. Colonic and hypogastric nerves convey the peripheral excitation respectively from colon and bladder. Intermesenteric nerve sends in peripheral excitatory input from colon and central from spinal cord. This finding suggests that the excitation of the prevertebral ganglia originates from not only spinal cord as claimed tranditionally, but also the peripheral organs. The latter exits stronger effect than the former. It seems that IMG is an integration neurocenter rather than a simple signal relay station from the central nervous system to peripheral effectors.

关 键 词：突触电位 肠系膜下神经节 神经元 兴奋 

分 类 号：R338.1[医药卫生—人体生理学]