大鼠延髓腹外侧表面呼吸调节化学感受区的感受机制分析  

On the Chemoreception Mechanism of the Ventrolateral Medullary Surface in Rats

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作  者:田国锋[1] 

机构地区:[1]上海医科大学生理学教研室

出  处:《生理科学进展》1995年第2期145-148,共4页Progress in Physiological Sciences

摘  要:用免疫组化(HRP)、H+表面透入、核团微量注射、微电泳及损毁等方法探讨了延髓腹侧表面中枢化学感受机制。结果表明它与其浅层核团:斜方体核、外周橄榄腹外侧核(LVPO)、斜方体后核、巨细胞旁外侧核和外侧网状核等有神经结构联系。表面H+可能被上述核团的突起或胞体感受。非呼吸相关神经元(LVPO)与呼吸相关神经元(面神经后核,NRF)同样可能参与中枢化学感受而调节呼吸活动。This work is to investigate the mechanism of central chemoreception of the ventral medullary surface in respiratory regulation in rats. A series of methods including immunohistochemical(HRP),H+ permeation, microinjection, microiontophoresis,and destruction of related nuclei were used. Results showed that nucleus of trapezoid, lateroventral periolivary nucleus(LVPO), retrotrapezoid nucleus, lateral paragigantocellular nucleus and lateral reticular nucleus have the neural structural relations with the surface. Their processes or their soma might be receptive to the H+ applied to the ventral surface.It also demonstrated that both non-respiration related neuron(LVPO)and respiration related neuron(nucleus retrofacialis, NRF)might play roles in central chemoreception in respiratory regulation.

关 键 词:中枢化学感受 延髓腹侧面 呼吸 化学感受器 

分 类 号:R338.22[医药卫生—人体生理学] R339.172[医药卫生—基础医学]

 

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