丘脑中央下核在痛觉感受与痛觉调制中的作用  

The Roles of Thalamic Nucleus Submedius in Nociception and pain Modulation

作　　者：唐敬师[1] 袁斌[1] 张玉秋[1] 张笋 

机构地区：[1]西安医科大学神经生理研究室

出　　处：《生理科学进展》1995年第4期312-316,共5页Progress in Physiological Sciences

摘　　要：本文结合笔者的工作，综述了近年来关于丘脑中央下核（Ｓｍ）在痛觉感受与痛觉调制中作用的研究。结果表明，它可能主要与痛觉的情绪激动成分有关，而且Ｓｍ－ＶＬＯ－ＰＡＧ可能构成一个痛觉调制的通路，通过脑干下行抑制系统在脊髓水平调制伤害感受性输入，从而产生痛觉的负反馈性调节。Recent studies on the roles of thalamic nucleus submedius(Sm)in nociception and pain modulation were reviewed in this article in combination with own our works.Results of these studies showed that Sm may be in volved in affecti ve- motivational aspects of pain,and that Sm-VLO-PAG may constitute a pathway of nociceptive modulation which may depress the nociceptive inputs at the spinal cord level via the brain-stem descending inhibitory system,thereby mediate a negative feedback regulation of pain.

关 键 词：丘脑 中央下核 伤害性感受 痛觉 调制 

分 类 号：R338.24[医药卫生—人体生理学] R338.3[医药卫生—基础医学]