正常成年猫多导程视觉诱发电位研究  

A STUDY OF THE MULTI-CHANNEL VISUAL EVOKED POTENTIALS IN ADULT CATS

作　　者：蔡浩然[1] 王伟[1] 周毅丁[1] 李少敏[1] 

机构地区：[1]北京医科大学儿童视觉研究中心

出　　处：《生物物理学报》1995年第4期563-569,共7页Acta Biophysica Sinica

基　　金：国家自然基金

摘　　要：用平面均匀闪光和棋盘格图形翻转刺激，研究了１７只正常猫的多导程视觉诱发电位（ＶＥＰｓ），主要结果为：１．图形刺激引起的Ｐ－ＶＥＰ波形为两个正相成份（Ｐ１和Ｐ２）夹着一个负相成份（Ｎ１）组成“Ｗ”型的波复合；而平面均匀闪光引起的Ｆ－ＶＥＰ则为两个负相成分（Ｎ１和Ｎ１）成分夹着一个正相成分（Ｐ１）构成“Ｍ”型的波复合．这两种ＶＥＰ均表现出明显的双眼总和现象，而且Ｐ－ＶＥＰ的总和率大于Ｆ－ＶＥＰ的。２．Ｐ－ＶＥＰ在头颅表面的分布是左右对称的，以在枕中线部位电极记录到的电位最大，距离中线越远，其电位越小。而Ｆ－ＶＥＰ则在中线的电位最小，而两侧电极记录到的电位反而更高，分布也是左右对称的。３．随刺激的空间频率增加，Ｐ－ＶＥＰ的峰潜伏期逐渐延长；振幅则以０．１ｃ／ｄｅｇ的刺激所引起的为最高，然后随刺激空间频率的升高而下降。４．以半视野图形进行刺激，各导程的Ｐ－ＶＥＰ仍为“Ｗ”型，但振幅则明显低于全视野刺激，并且当鼻侧视网膜受刺激时，其反应均大于颞侧受刺激。Multi-channel P-VEPs and F-VEPs were studied in 17 adult Cats. Thefollowing adults were obtained:1. The P-VEP wave complex consists of triple positive, negahve, and positive components (W-type). The F-VEP wave complex elied by plane homogenoous flash also containS three component, but the sequence is negatiVe-positive - negahve (M-type). Both typesof VEP showed clearly .binocular stnnmation.2. The P-VEPs obtained from different channels were symmetrically distributed on twosides of the scalp. The maxial amplitude was recorded from the midline chalmel and theamplitudes fell off symmetrically on both sides of the head. However, the amplitude ofF-VEP rmuled from the brine channel was minimum and those recorded from bilanteralchannels were larger as Well as symmetrical.3. When the spatial fequency (SF) of the cheCkboard was inrmed, the peak haplidtthe was delayed. The amplitude of the P-VEP was the highest at the 0.1c/deg SF and thendaised with increasing SF of stimulation.4. The P-VEP COmplexeS from different channels remained W-type, when the half fieldstimulation was used. In companion with the whole field stimulation, the amplitude was muchsmallers. The asponses elied with the striation of nasal retina were larger than those elicital with the stimulation of temporal retina.

关 键 词：视觉生理 多导程 视觉诱发电位 猫 动物实验 

分 类 号：R339.14[医药卫生—人体生理学]