槐耳菌质成分对小鼠免疫功能的影响  

The Effect of Trametes robiniophila Murr. (TRM) Substantial Composition on Immune Function of Mice

作　　者：陈慎宝[1] 丁如宁[1] 

机构地区：[1]南京医科大学微生物学教研室,南京210029

出　　处：《食用菌学报》1995年第1期21-25,共5页Acta Edulis Fungi

摘　　要：中国古代著名药用菌槐耳（Trametes robinpphila Murr.）在营养基质上进行固体发酵,产生槐耳菌质,从中提取的清膏及进一步提取的蛋白多糖,都有显著的抑制动物体内瘤和延长生命等作用,抑癌率可达50％左右.清膏治疗中晚期原发性肝癌总有效率达75.71％,它们具有促进多种免疫功能的作用,是良好的生物反应调节剂（BRM）,并有可能进一步扩大其适应症.Through solid fermentation in nutrient substratum, Trametes robiniophila Murr. (TRM), used as a famous medicinal fungi in ancient china, produced fungal substance from which clear paste and further isolated proteoglycan had been extracted. Both clear paste and proteo'glycan had tumor-inhibition effect on experimental animals and prolonged the life of infected animals And the tumor inhibition rate ia about 50%. Patients with middle or later period primary hepatoma treated with the paste, had got a total efficient rate of about 75%. Both the TRM clear paste and the proteoglycan promoted various immune functions. They are good biological response modifier and may be used to treat other adaptive diseases.

关 键 词：槐耳 菌质 生物反应调节剂 小鼠 免疫 

分 类 号：R282.710.7[医药卫生—中药学]