大熊猫胃肠道内分泌细胞分布型的研究  

THE DISTRIBUTION OF ENDOCRINE CELLS IN THE GUT MUCOSA OF THE GIANT PANDA

作　　者：杨贵波[1] 陈茂生[1] 邓泽沛 王平[1] 

机构地区：[1]北京大学生命科学学院

出　　处：《兽类学报》1995年第1期4-10,共7页Acta Theriologica Sinica

摘　　要：本文用ＰＡＰ法对３只大熊猫胃底、幽门腺区、十二指肠、空肠、回肠、结肠和直肠的五羟色胺、生长抑素、胃素、胆囊收缩素、神经降压素、胃动素、抑胃多肽、胰高血糖素、血管活性肠肽和内啡肽的ＩＲ细胞进行了研究。结果表明，大熊猫胃肠道粘膜上皮中具有前八种ＩＲ细胞。对７年龄个体胃肠各段相对数量的比较和各段内分布情况的现实结果表明，除五羟色胺ＩＲ细胞在空肠分布较多外，大多数种类的ＩＲ细胞集中分布于幽门区和十二指肠；幽门区的ＩＲ细胞主要集中在腺颈部附近。与已有的研究比较，大熊猫胃肠道中五羟色胺、胆囊收缩素、胰高血糖素、生长抑素ＩＲ细胞的分布型较为特殊，可能与其特殊的食性和分类地位有关。Endocrine cells contahing 5-hydroxytryptamine,somatostatin, gastrin, cholecystokinin,neurotensin,motilin,gastric inhibitory polypeptide,glucagon, vasoactive in testinal peptide,and endorphin in the mucosa of the ftindus,pylorus,duodenum,jejunum,ileum,colon,and rectum of 3 giant pandas were studied by PAPmethod to gain an insight into the adaptive characteristics for the special feeding habit.The former 8 kinds of endocrine cells were detected in the mucosa of the 75 day-old and7 year-old giant pandas.Quantitative analyses of inter-and intra-segmental differencesin the freqtiency of occurrence of each kind of the endocrine cells in the stomach andsmall intestine of the 7 year-old individual showed that:5-HT immunoreactive cellsoccur most frequently in the jejunum,which has not been observed in the othermammals. Cholecystokinin、gastrin、somatostatin immunoreactive cells occur mostfrequently in the pyloric antrum,while motilin immunoreactive cells occur mostfreqtiently in the duodenum,gastric inhibitory peptide、neurotensin、glucagonimmunoreactive cells occur most frequently in the ileum. Endocrine cells distributeprincipally in the lower two-thirds of the fundic gland,near the neck portion of thepyloric gland,and in the crypts of Lieber-kuhn's gland with the exception of 57%ofneurotensin immunoreactive cells distribute in the mucosa of the villus. These resultsindicate specific patterns of distribution of the endocrine cells in the mucosa of the giantpanda,which might be related both to their specific feeding habit and their taxonomicposition.

关 键 词：大熊猫 胃肠道 内分泌细胞 分布 

分 类 号：Q959.838[生物学—动物学]