实验性感染性休克肺损伤的显微和超微结构观察  

Morphologic Study of Acute Lung Injury Induced by Septic Shock

作　　者：张建平[1] 朱锦祥[1] 张锡庆[1] 吴嘉伟[1] 朱雪明[1] 郭玉华[2] 

机构地区：[1]苏州医学院附属儿童医院外科 [2]苏州医学院电镜室

出　　处：《苏州医学院学报》1995年第5期829-831,999,共3页Acta Academiae Medicinae Suzhou

摘　　要：用肠穿孔和腹腔注入致病性大肠杆菌的方法复制幼猪腹膜炎所致感染性休克模型。观察休克晚期的肺组织形态改变。Spetic shock from intestinal perforation and intraperitoneal inoculation of live Escherichia coli bacteria in infant pigs was developed.The pig'right lung sections in terminal stage were examined by light and transmission electron microscopes.The light microscopic results showed that pulmonary congestion,widen intersitia and leucocyte sequestration were in a localized facshion.The ultrastructural observation demonstrated thd alteration in permeability of cell membranate structures, including alveolar epithelial,endothelial and interstitial cells.And the pathological changes of alveolar type Ⅱ cells were relatively more remarkable and diffusive than that of other cells.The study might reveal a direct morphologic evidence regarding to the pathogenetic mechanisms of acutr respiratory failure in septic shock.

关 键 词：感染性休克 休克 肺损伤 超微结构 

分 类 号：R631.402[医药卫生—外科学]