环磷酰胺冲击治疗儿童难治性肾病综合征30例疗效观察  

THE 0BSERVATI0N OF THE CVRATIVEEFECT ON 30 CRNS CVRED WITH CTX一PT

作　　者：沈卉[1] 刘同菊[1] 李秀梅 沈敏 

机构地区：[1]泰山医学院第一教学医院

出　　处：《泰山医学院学报》1995年第2期110-112,共3页Journal of Taishan Medical College

摘　　要：儿童难治性肾病综合征３０例。本文用环磷酰胺冲击（ＣＴＸ一ＰＴ）治疗。结果：近期疗效９０％，２０／３０例在第一疗程有效，２６／３０例在第二疗程有效，２７／３０在第三疗程有效。近期副作用：轻度脱发３例，恶心、呕吐２例，１例外周血ＷＢＣ降为２．８Ｘ１０９／Ｌ结果表明：ＣＴＸ一ＰＴ不失为一种治疗ＲＮＳ有效、副作用少的方法。This paper is to present the study of the CTX pulse therapy for 30 cases of CRNS. with a curative effect of ninty precent in the near future,Twenty of the thivty cases got the curative ef- fect in the first period of tveatmoent,twenty一six of the 30 cases in the second period and twenty一sev- en of 30 cases in the third one. The side effect in the near future shows that three cases have a shght tri- chomadesis,two cases with nauses and vomiting and one case WBC reduced to 2. 8X 1Oa/L. The resulf of the tveatment shows that CTX一PT is an effective method to cure RNS with less side effect

关 键 词：肾病综合征 环磷酰胺 冲击治疗 儿童 

分 类 号：R726.920.5[医药卫生—儿科]