肾小管酸中毒与肾结石  

Renal Tubular Acidosis and Renal Calculi

作　　者：赵立全[1] 翟德佩[1] 李扬[1] 

机构地区：[1]天津医科大学总医院肾科,300052

出　　处：《天津医药》1995年第1期34-35,共2页Tianjin Medical Journal

摘　　要：分析37例肾小管酸中毒(RTA)患者有关并发肾结石的资料。其中21例完全性远端RTA并发肾结石6例,12例不完全性远端RTA并发肾结石3例,4例完全性近端RTA未并发肾结石。提示远端RTA是肾结石常见原因之一。通过测定尿pH值,表明晨空腹第二次尿pH>6.0可作为筛选完全性和不完全性远端RTA的方法。8例远端RTA并发肾结石患者服用枸橼酸钾后尿钙明显减少(P<0.0005),揭示枸橼酸钾可预防肾钙性结石形成。As concerning in renal calculi,37 patients with renal tubular acidosis (RTA) were studied. Among them there were 6 patients with renal calculi in 21 complete distal RTA and 3 patients with renal calculi in 12 incomplete distal RTA, but there was no one renal calculus in all the 4 complete proximal RTA- It revealed that distal RTA was a common cause of renal calculus. The fasting morning 2nd voided urines pH were tested. The results showed that complete or incomplete distal RTA urine pH were usually greater than 6. 0. So urine pH test can be used as a screening test for distal RTA. After treating with oral potassium citrate the urine calcium levels were significantly decreased (P<0. 0005) in 8 distal RTA patients with renal calculi. The results suggested that potassium citrate may be able to prevent distal RTA patients from complicating calcium nephrolithiasis.

关 键 词：肾小管酸中毒 肾结石 尿 PH 枸橼酸钾 

分 类 号：R692.4[医药卫生—泌尿科学]