人总体水的GC／MS法测定  

THE MEASUREMENT OF TOTAL BODY WATER(TBW)BY GC/MS

作　　者：江骥[1] 焦颖 李晓明[1] 胡玉芳[1] 杨则宜 王世真[1] 

机构地区：[1]北京协和医院,国家体委运动医学所

出　　处：《同位素》1995年第1期6-11,共6页Journal of Isotopes

摘　　要：采用自化学电离ＧＣ／ＭＳ技术，以氘水为人体内示踪剂（０．６ｇ／ｋｇ体重），测定了氘水在５例成人体内的平衡速度，并比较了在血、尿和唾液样品中的异同。根据摄入氘水后２．５、３．０、３．５小时唾液中同位素的平均稀释程度计算了一组正常中国成人体内总体水（ＴＢＷ）等参数。Equlibrium speeds of D_2O administered orally in 5 normal adults were measured with the technique of self-chemical ionization on GC/MS.The variations of D_2O in serum,urine and saliva werecompared too.The total body water(TBW)in 6 normal Chinese adults were determined according tothe average dilution in the saliva at 2.5,3 and 3.5 hours after D_2O intake at the dosage of 0.6g/kgbody weight.

关 键 词：人总体水量 体液 氘水 气相层析/质谱 水代谢 

分 类 号：Q493.7[生物学—生理学] Q585