陕西汉族人群备解素因子B的遗传多态性研究  

BF POLYMORPHYISM IN HAN POPULATION OF SHAANXI

作　　者：薛明战[1] 林田[2] 

机构地区：[1]西安医科大学妇幼卫生系,西安710061 [2]西安医科大学生物学教研室

出　　处：《西安医科大学学报》1995年第3期266-268,共3页Journal of Xi'an Medical University(Chinese)

摘　　要：本文用琼脂糖凝胶高压电泳及免疫固定技术检测了326例陕西汉族人群的备解素因子B(简称Bf)的遗传多态性。在该人群中检出了BfSS、BfFS、BfFF及BfSS 07 4种Bf表型,他们的频率分别为0.7883,0.1687,0.0245及0.01 85。Bf的3个等位基因Bf~*F,Bf~*S和Bf~*S07频率分别为0.8819,0.1089及0.0092。这一结果与大部分已检测的中国汉族人群的Bf分布特点相似,而与白种人和黑种人的Bf多态性分布有所不同。326 healthy individuals of Han population in Shaanxi were typed for Bf polymorphism, using high voltage agarose gel electrophoresis and subsequent immunofixation. Four Bf phenotypes, BfSS, BfFS, BfFF and BfSSO7, were found in this population. The frequencies of them were 0. 7883,0. 1687,0. 0245 and 0. 0185 respectively, and Bf alle-les, Bf S, Bf F and Bf S07, were 0.8819, 0.1089, and 0.0092 respectively. Compared with others, this result was similar to many Chinese populations, but significantly different from Negro and Caucasian.

关 键 词：备解素因子B 遗传多态性 琼脂糖电泳 免疫固定 

分 类 号：R392.11[医药卫生—免疫学]