急性高原反应、高原肺水肿患者支气管肺泡灌洗液的研究  

A Study on the bronchoalveolar lavage fluid of acute altitude stress and high allitude pulmonary

作　　者：洪青元[1] 牟信兵[1] 朱素琼[1] 罗登成 

机构地区：[1]西藏军区总医院高山病研究中心

出　　处：《西藏医药》1995年第2期1-3,共3页Tibetan Medicine

摘　　要：为了探讨急性高原病的发病机理，本文观察了急性高原反应、高原肺水肿及同海拔健康者各10名支气管肺泡灌洗液的改变，发现肺水肿患者肺泡灌洗液中含有大量的蛋白质，红细胞及白细胞，同时也含有大量的免疫球蛋白（IgC、IgA、IgM）和补体C3、C4；而急性高原反应患者肺泡灌洗液改变同高原健康人相比无异常发现，提示高原肺水肿患者肺循环有“漏孔”存在，高原肺水肿是一种高渗性肺水肿。而急性高原反应发病中未有肺泡腔渗漏发现。To explore the pethogenic mechanism of acute mountain sickness we per formed bronchcalveolar lavage in 10 patients with acute altitude stress, 10 potients with high altitude pulmonary edema (HAPE)in Lhasa (above as level 3658M)and 10 high altitude healthy subjects wee used as control. It is discovered that the fluid of HAPE potients contained marked increase in protrein,erythrocyte and leukocyte, also contalned the immunoglobulin,complement c3,c4. But the fluid of acute altitude stress patients were as the control. It indicatal that HAP involved ″pore leak″in the pulmonary circulation,HAP was a hypertonic pulmonary edema.

关 键 词：缺氧 急性 高原病 支气管 肺泡灌洗液 肺水肿 

分 类 号：R594.3[医药卫生—内科学] R541.63[医药卫生—临床医学]