家兔动脉粥样硬化的高频心电图研究  

Experimental study on rabbits with atherosclerosis by high frequency electrocardiogram

作　　者：高书旺 杨惠彬[1] 高国杰[2] 

机构地区：[1]军事医学科学院卫生学环境医学研究所,300050 [2]解放军总医院

出　　处：《心电学杂志》1995年第1期16-18,共3页Journal of Electrocardiology(China)

摘　　要：将雄性大耳白家兔分为实验组和对照组各10只,分别饲以高脂饲料和普通饲料120天.病理观察结果显示,实验组动物全部形成不同程度的动脉粥样硬化(AS),对照组只有2只出现,组间有极显著性差异(P<0.01).心电检测显示,高频心电图、频谱心电图于实验第60天组间出现显著性差异(P<0.05),常规心电图至第120天仍无明显改变.提示高频心电图、频谱心电图在对冠心病的诊断方面均较常规心电图敏感.20 male rabbits were divided into 2 groups, i. e. the experimental group and the control group, 10 for each.The animals were fed with high lipid feed and usual feed respectively for 4 months. By the end of the experiment, all the animals of the experimental group had developed atherosclerosis in different degrees, but only 2 of the control group. Sharp difference existed between the two groups(p<0. 01). During the experiment, electrocardiogram (ECG), high frequency electrocardiogram (HFECG) and frequency spectrum electrocardiogram (FCG) were taken once a month. The results showed that obvious difference was observed between two groups in HFECG and FCG 2 months later, but not so in ECG till the, end of the experiment. HFECG or FCG seems to be more sensitive to the diagnosis of early coronary heart disease than ECG.

关 键 词：心电图 频谱心电图 家兔 冠心病 

分 类 号：R540.41[医药卫生—心血管疾病] R541.404[医药卫生—内科学]