昂丹司琼临床应用的药物利用评价  

Retrospective Evaluation on the Clinical Use of Ondansetron

作　　者：吕纹[1] 徐珺[1] 陈开盛[1] 李大魁[1] 王强[2] 

机构地区：[1]北京协和医院药剂科,北京100730 [2]华西医科大学临床药学专业

出　　处：《药物流行病学杂志》1995年第4期230-232,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：昂丹司琼(ondansetron)为一种强效、高选择性的5-HT_3受体拮抗剂,主要用于预防和治疗抗肿瘤化疗和放疗所引起的恶心和呕吐.本文参照国外有关昂丹司琼的使用标准,对我院65例曾服用过昂丹司琼的患者进行了用药情况的回顾性评价,其中符合治疗适应症标准的占76.9%,符合剂量及用法标准的占73.8%.通过药物利用评价,有助于提高昂丹司琼的用药水平,使之应用更加经济、合理、规范化.Ondansetron is a potent, highly selective 5-HT_(3) receptor antagonist, It is used for the prevention and management of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy. A retrospective evaluation on ondansetron in 65 inpatients was conducted over a six month period. The results revealed that 76. 9% of the orders met the criteria of the therapeutic indication. Criteria for dosage and administration were met in 73. 8% of orders. An evaluation on the use of ondansetron is helpful in promoting the rational use of this agent.

关 键 词：昂丹司琼 枢复宁 止吐药 药物利用评价 

分 类 号：R975.4[医药卫生—药品]