爬行足迹分析测定动物肢体负重功能  

WALKING TRACE ANALYSIS EVALUATE LOADING OF THE HIND LEGS OF RATS

作　　者：顾延[1] 戴克戎[1] 裘世静[1] 戴闽 

机构地区：[1]上海第二医科大学附属生物力学研究室

出　　处：《医用生物力学》1995年第1期46-50,共5页Journal of Medical Biomechanics

摘　　要：目前还没有定量测定动物肢体负重状况的可靠方法，爬行足迹分析是通过测定动物爬行时足印的大小从而反映其爬行时肢体负重情况的半定量测定法。选用一侧跟腱切除模型为实验对象，将大鼠后肢在显影液中浸泡后，使其爬行通过感光胶片，即在胶片上获得清晰的大鼠爬行时的足印，测量并计算大鼠足印大小（Ｓ）和两侧足印大小的比值（Ｓｒ）。结果显示：大鼠一侧跟腱切除后，很长时间内，其双侧Ｓ值有显著差异（Ｐ＜０．０１）；Ｓｒ值则随时间延长逐渐接近１。反映了大鼠双侧后肢负重在跟腱切除后有显著差异并随肢体修复逐渐接近的过程。实验证明：爬行足迹分析能较准确地反映动物肢体的负重变化情况。There is still no proper method to measure the loading on legs of an animal.Walking trace analysis is used as a quantitative method in this study. Ten rats having their left calcaneal tendons transected were used. The feet of rats were dipped in the developing fluid, and let them crawl over the film to get the foot prints. The foot prints were then measured to evaluate the loading of the hind legs. The results showed that the foot prints of the operated left hind legs were smaller than the opposite ones. The rate of the foot print area of the two sides(Sr) was calculated and showed siguificant difference(P<0.01) for a rather long period and gradually approaching the value 1, as the operated leg healed up as time goes on. Hence we conclude that walking trace analysis can evaluate the loading of animal leg representing the actual condition.

关 键 词：足迹分析 实验动物 肢体负重 

分 类 号：Q66[生物学—生物物理学]