镍钛形状记忆合金细胞相容性和生物力学兼容性的改进  

IMPROVEMENT OF CYTOCOMPATIBILITY AND BIOMECHANICAL COMPATIBILITY OF NITI SHAPE MEMORY ALLOYS

作　　者：L’H Yahia S.Lombardi N.Hagemeister G.Drouin C.H. Rivard M .Assad Okuyaman(Biomechanical-Biomaterials Research Group, Biomedical Engineering Institute, Ecole Polytechnique de Montreal,Canada)(Department of Orthopaedic Surgery,Hospital St.Justine, Montreal, 

出　　处：《医用生物力学》1995年第2期19-25,共7页Journal of Medical Biomechanics

摘　　要：镍钛记忆合金（ＮｉＴｉ）生物材料器件的发展，迫切要求研究和提高其细胞相容性和生物力学性能。依据美国材料测试标准协会（ＡＳＴＭ）的标准，我们研究表明：ＮｉＴｉ的细胞毒性比纯钛、Ｔｉ６Ａ１４Ｖ和３１６Ｌ不锈钢大，在ＮｉＴｉ表面作聚合四氟乙烯高离子（ＰＰＴＦＥ）喷涂。可降低ＮｉＴｉ合金的细胞毒性，提高其抗腐蚀力。各种热处理方法可改善其疲劳性能，循环拉伸强度试验可测出其超弹性性能的衰减。For the development of Nickel Titanium NiTi)biomaterial devices,the study and improvement of cytocompatibility and biomechanical performances are of prime importance. Following the guidelines of the American Society for Testing Materials (ASTM), our study established that the cytotoxicity of NiTi was worse than that of pure Ti, Ti6A14V and 316L stainless steel. The deposition of plasma polymerized tetrafluoroethylene (PPTFE) thin film on NiTi surface improved cytotoxicity and corrosion resistance of NiTi alloys. The fatigue propertics were improved by various heat treatments and the degradation of the superelastic properties were tested by cyclic tension-tension tests.

关 键 词：镍钛合金 植入物 生物力学 韧带 细胞相容性 

分 类 号：R318.08[医药卫生—生物医学工程]