全血粘度、红细胞粘弹性和触变性在下肢深静脉血栓形成发病机制中的作用  

STUDY ON PATHOGENETIC ROLE OF THE BLOOD VISCOSITY,VISCO-ELASTICITY AND THIXOTROPY IN LOWER EXTREMITY DEEP VENOUS THROMBOSIS

作　　者：杨景文[1] 胡余[1] 侯福祥[1] 张培华[1] 

机构地区：[1]上海第二医科大学附属第九人民医院血液内科,上海血液学研究所血流变血栓研究室,上海第二医科大学附属第九人民医院血管外科

出　　处：《医用生物力学》1995年第4期201-204,共4页Journal of Medical Biomechanics

摘　　要：本文对７１例下肢深静脉血栓形成患者，经下肢静脉造影确诊后，全部进行了血液流变学──全血粘度、红细胞粘弹性和触变性测定。测定结果显示，患者的全血粘度增加，红细胞弹性减低及触变性－滞环各个点的数值均增高，与正常对照组相比（ｘ±ＳＤ）差异有非常显著性（Ｐ＜０．０１），但滞环的面积－能量的消耗，两组相比（ｘ±ＳＤ）差异无显著性（Ｐ＞００５），提示全血粘度、红细胞粘弹性和触变性的改变是参与了血栓形成的因素之一。Hemorheology including blood viscosity,visco-elasticity and thixotropy has been studied in 71 patients with deep vein thrombosis in lower extremity.All the cases were confirmed by phlebography.The results showed high blood viscosity,decreased in red blood cell elasticity and increase value on each point of thixotropy-Hysteresis Loop in all.As compared with the control group,there is significant difference(p<0.01).However,the area of the Hysteresis Loop and the energy consumption have no remarkable difference(p>0.05)between the two groups.It reveals that the blood viscosity,red blood cell visco-elasticity and thixotropy take part in the formation of thrombosis.

关 键 词：深静脉血栓 全血粘度 粘弹性 触变性 下肢 LDVT 

分 类 号：R543.602[医药卫生—心血管疾病]