利福定不同晶型和制剂的生物利用度  

STUDY ON RELATIONSHIP BETWEEN BIOAVAILABILITY AND CRYSTALLINE FORMS AS WELL AS DOSAGE FORMS OF RIFANDIN

作　　者：冯军 

机构地区：[1]长征制药厂,乐山四川614006

出　　处：《中国医药工业杂志》1989年第11期498-501,共4页Chinese Journal of Pharmaceuticals

摘　　要：利福定为一多晶型化合物。实验表明由Ⅰ型或Ⅳ型晶型的利福定制成的胶囊剂有较高的生物利用度和疗效。Rifandin (isobutyl-piperaginyl-rifamycin SV) is a polymorphousCompound with at least four types. The experiments showed that its capsules made of type I or IV had betterbioavailability and therapeutic efficacy.

关 键 词：利福定 生物利用度 晶型 制剂 

分 类 号：R978.19[医药卫生—药品]