锌或锡参与下末端环氧化合物的选择性烯丙基化反应  

Zinc-and Tin-Mediated Selective Allylation of Terminal Epoxides

作　　者：邓道利[1] 陆忠辉[1] 

机构地区：[1]中国科学院上海有机化学研究所金属有机化学开放实验室,上海200032

出　　处：《有机化学》1995年第1期95-99,共5页Chinese Journal of Organic Chemistry

摘　　要：烯丙基溴和金属锌或锡可成功地将末端环氧化合物1-锅法合成高烯丙基醇2和双高烯丙基醇3。还研究了环氧化合物取代基的影响,并提出了此烯丙基化的反应途径。Allylation of terminal epoxides 1 can be carried out successfully by allyl bromide and metallic zinc or tin in a novel one-pot synthesis to give the homoallylic alcohols 2 and bishomoallylic alcohols 3. The effect of substituents on epoxides was studied. The reaction pathway of this allylation was also suggested.

关 键 词：锌 锡 环氧化物 烯丙基化 烯丙基醇 

分 类 号：O623.412.1[理学—有机化学]