1-硫代-1-磷杂-2,6,7-三氧杂双环[2.2.2]辛烷基-4-亚甲基硫醚及其亚砜的合成  

Study on the Synthesis of 1-Sulfur-1-Phospha-2,6,7 Trioxabicyclo [2.2.2] Octyl-4-Methyl Thioethers and Its Sulfoxides

作　　者：李玉桂[1] 王新龙[1] 朱雪峰[1] 周汉杰[1] 

机构地区：[1]南开大学元素有机化学研究所,天津300071

出　　处：《有机化学》1995年第1期57-60,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金

摘　　要：本文通过Williamson反应,合成了9个双环笼状硫代磷酸酯的硫醚衍生物3a～i。以3b,3c为例研究了硫醚衍生物的还原性,并合成相应的亚砜化合物4b,4c。讨论了亚砜化合物的立体化学。Nine new thioethers of caged bicyclic thiophosphates 3a- i were prepared by Williason Reaction. Oxidation of the thioethers 3b and 3c gave the corresponding sulfoxide 4b and 4c which containning one chiral sulfur atom. The stereochemistry of the sulfoxide was also discussed.

关 键 词：双环 笼状 硫醚 亚砜 合成 磷酸脂 

分 类 号：O627.51[理学—有机化学]