不同时辰电针对大鼠脑内甲硫氨酸脑啡肽含量的影响  

Effects of Electroacupuncture at Different Time on Brain Methionine-Enkephalin Contents in Rats

作　　者：王友京[1] 王双坤[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》1995年第3期26-28,共3页Acupuncture Research

摘　　要：本文分别比较5：00、11：00、17：00和23：00四个时辰大鼠延桥脑、下丘脑、海马、中脑、纹状体和皮层内MEK基础水平及其电针的影响，结果表明，各脑区内MEK基础水平有昼夜节律变化，不同时辰电针对各脑区内MEK的水平有不同效应。The basic level of methionine-enkephalin (MEK) in rat medulla oblongata plus Pons was thehighest at 05: 00 o'clock and the lowest at 23: 00. In both the hypothalamus and the striatum at 05: 00 MEK levles were respectively higher.than those at 11: 00, 17: 00 amd 23: 00. In both thehippocarnpus and the midbrain at 05: 00 and 23: 00 they were respectively higher than those at 11:00 and 17: 00. In the cortex it was higher at 05: 00 than those at 11: 00 and 17: 00Electroacupuncture (EA) at 05: 00 increased the MEK content in the tnedulla oblongata pluspons and decreased the MEK content in the hypothalamus. EA at 11: 00 produced decreases of MEKconcentrations in the medulla oblongata plus pons and the midbrain and increases of MEK content inthe cortex. At 17: 00 it increased the MEK level in the hypothalamus and at 23: 00 it reduced thelevel of MEK in the hippocampus.The results suggest that there are very marked circadian rhythrns in the MEK basic levels of thesix discrete hrain regions observed and EA at different hours produces different effects on brain MEKlevels.

关 键 词：时辰 电针 甲硫氨酸脑啡肽 大鼠 

分 类 号：R245.97[医药卫生—针灸推拿学]