针刺对创伤性休克大鼠不同脑区脑啡肽含量的影响  

Effect of Acupuncture on the Contents of Enkephalins in Different Brain Regions of Rats with Traumatic Shock

作　　者：马春红[1] 谭连红[1] 王传英 赵相杰 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》1995年第3期33-35,共3页Acupuncture Research

基　　金：国家自然科学基金

摘　　要：本实验采用结扎大鼠双后肢致创伤休克为模型，用放射免疫方法测定休克前后海马、纹状体、下丘脑、间脑和脑干脑啡肽变化。实验结果如下：（1）创伤性休克时，五个脑区甲硫脑啡肽含量无明显变化，针刺后甲硫脑啡肽含量亦无明显变化。（2）休克动物各脑区亮脑啡肽含量有升高趋势，电针后下丘脑亮脑啡肽含量显著降低。提示在本实验系统内，创伤性大鼠休克的发生可能与中枢亮脑啡肽系统的功能活动有关。而针刺抗休克作用可能是通过中枢LEK水平降低导致微循环功能的改善，使血压回升来实现的。The study was carried out on the animal model of traumatic shock which induced by ligating bilateral hind legs. The contents of enkephalins in-hippocampus, striatum, hypothalarnus. diencephalonand brain stem were determined with radioimmunoassay. The results show that: (1 ) when traumatic shock occurs. the contents of Met-enkephalin are not obvious change in the above 5 brain regions,and also not significant change after acupuncture; (2) there is a tendency to increase the content ofLeu-enkephalin in each brain region described above of shock animal, while it is decreased in hypothalarnus after acupuncture. The result suggests that the occurrence of traumatic shock may be related tothe functfonal activities of Leu-enkephalinergic system in the central nervous systern; the anti-shock ofacupuncture may be through a decrease in the level of central Leu-enkephalin to improve micro-circu-lation and raise the blood pressure

关 键 词：创伤性休克 电针 甲硫脑啡肽 亮脑啡肽 

分 类 号：R246.2[医药卫生—针灸推拿学]