针灸抑制胆色素结石形成的临床和实验研究  

Clinical and Experimental Researches in the Inhibition of Bile Pigment Lithogenesis by Acupuncture and Moxibustion

作　　者：张时宜[1] 陈汉平[1] 桂金水[1] 徐长生[2] 朱培庭[2] 曹中平[2] 

机构地区：[1]上海市针灸经络研究所,上海200030 [2]上海中医药大学附属龙华医院,上海200032

出　　处：《针刺研究》1995年第3期40-45,共6页Acupuncture Research

摘　　要：临床以胆囊切除、胆总管切开置“T”管引流的病人为对象，通过针刺不同腧穴四组并同空白对照组相比较，结果观察到肝俞、期门等俞募配穴组能非常显著地促使肝胆汁的分泌和排泄，其即时效应优于其它各针组，而空白对照组肝胆汁泌出量则随时间的推移逐步减少。实验以豚鼠复制胆色素结石模型，证实针刺或艾灸动物“穴位”能显著降低胆汁中胆红素含量和β葡萄糖醛酸酶活性，确能显著地抑制动物由致石饲料诱发的胆石形成。并观察到致石饲料能造成肝脂变性，针灸还能抑制肝脂肪变性的进程。Clinical subjects were the patients in whom cholecystectomy and choledochotorny were performedwith T tube drainage. Four groups of acupoints were established according to different point prescriptions. Under the strict control of experimental conditions and fixation of electrical acupuncture stimulation parameters- the changes of hepatic bile output were observed in five different stages before.during and after acupuncture, and compared with those in control group not treated by acupuncture.The results showed that electrical acupuncture of Ganshu (Back Shu point ) (GB 18 ) and Qimen(Front-Mu point ) (LI 14 )could obviously promote the secretion of hepatic bile. The immediate effectwas superior to that in other groups. ln a group not treated by acupuncture - hepatic bile output gradually decreased as time went on.In animal experiment. a rnodel of bile pigrnent lithogenesis was rnade in gulnea plg. The' animalswere randomly divided into five groups of control, sirnultaneous acupuncture' simultaneous moxihustion, re-acupuncture after one week and re-acupuncture after two weeks. The results indicated thatelectrical acupuncture or moxibustion of relevant acupoints such as Ganshu (GB 18) and Qimen (LI14 ) could really very effectively inhihit the animal lithogenesis caused by lithogenous food. A tendencywas observed towards that the earller acupuncture was perforrned, the better the preventive effect onlithogenesis. In the influence on lithogenous bile, both acupuncture and moxibustion could reduce thecontents of biliary total bilirubin and free bilirubin and the activity of hiliary 8-glycuronidase.Acupuncture also produced an effect in lowering hepatic 8-glycurouidase but moxibustion didh't. Hepatohistological observation showed that lithogenous food could also cause fatty degeneration of Iiver.and moxlbustion could markedly inhibit its progress. Both acupuncture and rnoxibustion didn't remarkably infIuence the content of serurn cholesterol.

关 键 词：针灸 胆色素结石 临床 实验 

分 类 号：R245.8[医药卫生—针灸推拿学]