产时催产素静脉滴注对脐动脉血血气分析影响的初步研究  

Preliminary Study of the Effect of Oxytocin Given by Intravenous Drip During Labor on Umbilical Aterial Blood Gas Analysis

作　　者：侯祖强[1] 刘淑云[1] 邓智明[1] 

机构地区：[1]青岛医学院第二附属医院检验科,青岛医学院第二附属医院妇产科

出　　处：《中国厂矿医学》1995年第3期163-166,共4页Chinese Medicine of Factory and Mine

摘　　要：本文以１０２例静脉滴注催产素的产妇和６０例正常分娩的产妇分别作为观察组和对照组，于胎儿娩出时即刻取脐动脉血进行血气分析测定．结果经统计学处理，发现：（１）观察组中碱剩余（ＢＥ）和细胞外液碱超（ＳＢＥ）两项负值增加，与对照组相比有明显差异（Ｐ＜０．０５）；（２）脐动脉血气各项指标与静滴时间（８ｈ内）无明显相关性（Ｐ＞０．０５）；（３）第二产程短于１ｈ的观察组ＢＥ和ＳＢＥ负值增加，与对照组比较有显著差异（Ｐ＜０．０５），（４）随第二产程的延长，两组ＰＨ、ＢＥ及ＳＢＥ均呈下降趋势，对照组下降极显著（Ｐ＜０．０１），而观察组的下降则无统计学意义（Ｐ＞０．０５），导致两组的ＰＨ值差异极显著（Ｐ＜０．０１）；（５）两组新生儿出生时一分钟Ａｐｇａｒ评分均≥８分．分析本实验结果，本文提出了合理地使用催产素不但有利于产程的正常进展，同时也有减轻随第二产程延长胎儿酸中毒加重的作用。有关理论和实验作了进一步探讨．A study on umbilical arterial blood gas analysis was made in 102 cases of parturient women given oxytocin by intravenous drip during labor with 60 cases of normal pregnancy as control. Immedintely alter each delivery,an umbilical arterial blood sampling was carried out for gas analysis. All the results were deal]ed with in detailed statistical analysis. They showed that there was a marked decrease of both BE and ABE values in the observation group compared with the control group (P<0. 05). The duration of time of intravenous drip(<8h)bore no relation to the parameters of umbilical arterial blood gas analysis(p>0. 05). With the prolongation of duration of the second stage oflabor,tbe values of the pH, BE and SBE showed a significant decrease in the control group itself (P<0. 01 )while not inthe observation group itslf. All the neonates in both groups had 1-minute Apgar scores≥8. Through this study theauthor advanced a new theory that the proper and rational use of oxytocn may be beneficial to alleviating fetal acidosis during the second stage of labor. The relevant theories and test results were further disussed.

关 键 词：催产素 静脉滴注 脐动脉 血液气体分析 分娩 

分 类 号：R714.4[医药卫生—妇产科学] R984[医药卫生—临床医学]