碘缺乏病区7～16岁人群血TSH含量动态观察  

A survey on Cytogenetics in children or mental retardation in iodine deficient areas

作　　者：周琳[1] 王秦宁[1] 安永清[1] 顾玉海[1] 马晓翠[1] 李勇[1] 

机构地区：[1]青海省地方病防治研究所

出　　处：《中国地方病学杂志》1995年第2期86-87,共2页Chinese Jouranl of Endemiology

摘　　要：用滤纸干血片法，对青海省碘缺乏病区７～１６岁人群进行连续三年甲状腺功能的动态研究，同时进行尿碘水平的观察。结果表明地甲病区ＴＳＨ对数均值逐年下降（Ｐ＜０．０１）．提示地甲病区人群机体内缺碘状况逐渐好转，提高碘盐浓度有利于控制一系列碘缺乏病的发生和发展。In this study 14 children with mental retardation and 14 normal subjects were examined. Appling low folio acid and low concentration of bovine serum cultures,we carried out the analysis ofchromosome G-band. The results showed that the chromosome aberration rates were 14. 43% forthe children with mental retardation and 6. 42% for the control group. The fragile sites incidencewere 85. 71% for children with mental retardation and 42. 85% for control group. Rates of chromosome aberration and expressive of fragile site were obviously higher in mental retardationgroup than those in nomal group(p<0.05).

关 键 词：碘缺乏症 滤纸干血片 免疫放射法 甲状腺激素 

分 类 号：R591.1[医药卫生—内科学] R599.9[医药卫生—临床医学]