大骨节病病区病户主食中T－2毒素检出报告  

Determination of T-2 toxin in the staple food from the sick families in Kashin-Back Disease (KBD) areas

作　　者：杨建伯[1] 孙殿军[1] 王志武[1] 

机构地区：[1]哈尔滨医科大学,中国地方病防治研究中心大骨节病研究所

出　　处：《中国地方病学杂志》1995年第3期146-149,共4页Chinese Jouranl of Endemiology

摘　　要：用ＥＬＩＳＡ法检查大骨节病病区病户面粉１５份，其中１０份Ｔ－２毒素为阳性，全距为２．０～１５４９．４ｎｇ／ｇ，均数４６８．７ｎｇ／ｇ；病区村、镇市售面粉８份，其中７份阳性．全距为２．５～８８５．３ｕｇ／ｇ，均数２４４．０ｎｇ／ｇ；基本控制病区样品４份，阳性１份，含量３５．６ｎｇ／ｇ。；非病区面粉１５份，阳性１０份，全距２．０～２４８．７ｕｇ／ｇ，均数８４．２ｎｇ／ｇ．在前述各地采集的大米、小米、黄米等粒状食粮均没有或仅有痕迹量的Ｔ－２毒素检出。对Ｔ－２毒素致大骨节病的病因学意义作了扼要讨论。We examined T-2 toxin content in wheat flour and the other grain from KBD areas and non-KBD areas using indirect competitive ELISA method based on monoclonal antibody. Of fifteen sick families of KBD areas, ten were found out T-2 toxin (range 2. 0￣1549. 4ng/g, mean 468.7ng/g); Of eight samples of wheat flour from the markets in the same KBD areas, seven were found out T-2 toxin (range 2.5￣ 885.3ng/g, mean 244.0ug/g); Of four samples of wheat flour from KBD controlled areas, one was found out T-2 toxin, and its content was 35.6ng/g; Of fifteen samples of wheat flour from non-KBD areas, ten were found out T-2 toxin (range 2. 0￣248. 7ng/g, mean 84.2ng/g). There was no T-2 toxin to be found out, or only to be trace in rice, millet, and blutinous millet collected in the areas mentioned above. Meanwhile, writers briefly discussed the significance of etiology of KBD caused by T-2 toxin.

关 键 词：大骨节病 面粉 T2毒素 地方病 

分 类 号：R684.1[医药卫生—骨科学]