钙硒对模拟克山病偏食喂养大鼠生长激素分泌的影响  

Effect of Calcium and Selenium on Growth Hormone of Rats fed with Keskan monotonous diet.

作　　者：郭成浩 孙波 康德仁[1] 邹亚彬 李成库[1] 王凡[1] 

机构地区：[1]长春白求恩医科大学地方病研究所

出　　处：《中国地方病学杂志》1995年第3期143-145,共3页Chinese Jouranl of Endemiology

基　　金：国家自然科学基金

摘　　要：模拟克山病偏食饲料及在这种饲料中补充钙和硒对大鼠生长和生长激素的影响。结果表明，这种克山病偏食饲料中除低硒外低钙特别突出，所饲大鼠血清钙水平及全血ＧＳＨ－Ｐｘ活性、血清总蛋白、生长激素明显低于常规食组。在克山病偏食饲料中单纯补钙或硒可明显改善大鼠生长状态及生长激素增多。表明钙和硒在病区粮偏食喂养大鼠所致生长迟缓方面及生长激素的释放中起重要作用。补充钙同时补充硒效果更好。The effects of mimic endemic monotonous diet (EM diet) susceptible to Keshan disease and that supplemented with Ca or/and Se on growth and growth hormone (GH) of rats were studied. The results demonstrated that Ca content in the EM diet was low prominently as well as Se. The serum Ca level.blood GSH-Px activity, serum total protein and GH of rats fed with EM diet were significantly lower than those of the rats fed with stock diet. When the EM diet was supplemented with Ca or Se alone the growth rate was significantly improved and GH increased. It is suggested that Ca and Se may play an important role in the growth and GH secretion of rats fed with EM diet. When the EM diet was supplemented with both Ca and Se the result was better.

关 键 词：克山病 钙 硒 生长激素 实验动物 地方病 

分 类 号：R542.302[医药卫生—心血管疾病]