尼群地平对食饵性家兔动脉粥样硬化的影响Ⅱ、血小板聚集性和血浆脂质过氧化的变化  

Experimental Study of Anti-atherosclerosis with Nitrendipine Ⅱ.Effects of nitrendipine on platelet aggregation and plasma lipid peroxidation

作　　者：涂玉林 杨小毅 刘德平 万载阳 

机构地区：[1]衡阳医学院心血管病研究所

出　　处：《中国动脉硬化杂志》1995年第4期312-313,320,共3页Chinese Journal of Arteriosclerosis

摘　　要：本文报道尼群地平对食饵性动脉粥样硬化家兔血小板聚集性和血浆脂质过氧化的影响。结果表明，尼群地平可抑制高脂血症诱导的血小板聚集性增加和脂过氧化物增多。提示尼群地平抗动脉粥样硬化作用，与这些变化有关。On the basis of observation that nitrendipine has a role of anti-atherosclerosis,the effects of nitrendipine on experimental atherosclerosis of rabbits was studied. Results showed that nitrendipine might inhibit the increase of platelet aggregation and lipid peroxidation induced by hypercholesterolemia,which suggest that the effect of nitrendipine antiatherosclerosis is linked with thses changes.

关 键 词：尼群地平 动脉粥样硬化 血小板聚集 过氧化脂质 

分 类 号：R972.4[医药卫生—药品] R543.505[医药卫生—药学]