临界高血压的自然转归及临床意义（131例17年随访）  

The Natural History of Borderline Hypertension (131 Cases Follow-up Study for 17 Years)

作　　者：谢良地[1] 吴可贵[1] 陈达光[1] 王耀华[1] 陈金水[1] 卢声远[1] 许能锋[1] 史习舜[1] 

机构地区：[1]福建医学院附属第一医院,福建医学院流行病学教研室

出　　处：《中国高血压杂志》1995年第2期158-161,共4页

摘　　要：１３１例临界高血压病人随访１７年；以地区、年龄、性别、职业１：１配对的正常人作对照，观察临界高血压病人的预后，发现６４．６２％的临界高血压病人发展成确诊高血压，２１．５４％病人的血压恢复正常，只有１３．８５％的临界高血压病人血压仍然在临界水平。临界高血压病人的总死亡率明显高于正常人。为正常人的２．３５倍，主要死因为脑卒中，占总死亡的４２．５％，发生脑卒中与脑卒中死亡的危险性分别为正常人的８．３４和１１．６１倍，揭示部分临界高血压病人可能需要处理以减少心脑并发症的发生。borderline hypertensive patients were followed up for 17 years.A cohort of normotensives matched with age, sex, region and occupation served as controls(1:1).It was found that 64.62 percent of borderline hypertensive patients developed into established hypertensives after 17 years' following up,while 25. 5% restored to normotensives and 13.8% remained unchanged.The total morbidity rate of borderline hypertensives was higher than that of normotensives, and the relative risk (RR) of total death in borderline hypertenslves was 2.35. The main causes of death was stroke, accounting for 42.5% of the total death. The relative risk rates of occurrence and death of the stroke were 8.34 and 11. 61 respectively.It was concluded that at least a part of borderline hypertensive patients need to be treated for the purpose to reduce the risk of cardiovascular complications.

关 键 词：高血压 预后 转归 

分 类 号：R544.101[医药卫生—心血管疾病]